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Old 01-07-2013, 11:02 AM   #1
Exodia
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Default H3N2 in the US vs H1N1 Elswhere

It seems like H3N2 is the strain causing a ton of ilness in the US/Canada this season, while the rest of the world is still battling with H1N1.

Any thoughts out there as to why this may be?

http://www.upi.com/Health_News/2013/...1371357507672/
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Old 01-07-2013, 11:18 AM   #2
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Isn't H3N2 known to be a particularly nasty strain? Seems like I read that once.
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Old 01-07-2013, 12:44 PM   #3
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Quote:
Originally Posted by drummagick View Post
Isn't H3N2 known to be a particularly nasty strain? Seems like I read that once.
In the 2003-2004 outbreak, it killed approx 3 out of 1000 people who contracted it. Of which, disproportionately children and elderly.
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Old 01-07-2013, 02:24 PM   #4
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Default Type A H1 is signifigintly more prevevant in EU than in thr US. 44% vs. 0.7%

Weekly influenza surveillance overview, 4 January 2013, week 52/2012
Surveillance reports - 04 Jan 2013

http://www.ecdc.europa.eu/en/publica...m.aspx?ID=1028
Available as PDF in the following languages:

This document is free of charge.

ABSTRACT
Weekly influenza surveillance in Europe for the 2012–2013 season started in week 40/2012. ECDC announced that the period of influenza transmission had started in week 49. In weeks 51 and 52, surveillance data in Europe are subject to particular delays and underreporting because of the holiday season so data should be interpreted with this in mind. In week 52, 20 of a potential 29 countries reported clinical data.

• During week 52/2012, four countries (France, Italy, the Netherlands and Norway) reported medium intensity transmission; geographic spread of influenza activity was reported as widespread by five countries (Belgium, Denmark, France, Norway and the UK (England)); and nine countries reported increasing trends.

• Of 375 specimens from sentinel patients, 25% were positive for influenza virus; a small decrease compared with 27% in the previous week. This may be related to a lower number of physician consultations over the New Year holiday.

Since week 40/2012, 46% of sentinel specimens were type A and 54% were type B, though the proportion of B viruses has decreased somewhat in recent weeks. Subtying of type A viruses has shown proportions of 56% A(H3) and 44% A(H1).

• Viruses characterised to date match well with the vaccine viruses.

• Countries undertaking surveillance of laboratory-confirmed severe influenza cases requiring hospitalisation are starting to report increasing numbers of such individuals.

Influenza activity continues to rise in a number of EU/EEA countries, especially in western Europe. Greater numbers of severe laboratory-confirmed cases are now being reported.

~
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Old 01-07-2013, 02:42 PM   #5
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Actually i don't know why that is.

It's probably not that unique. We can see different lineages in different places and the percentages change over time too.

The article above doesn't give percentages of A/H1N1 vs A/H3N2 in Europe.

Here's some numbers from the RIVM:
Quote:
In het griepseizoen tot nu toe (1 oktober tot en met 30 december 2012) zijn er door de CMR-peilstations 140 neus- en keelmonsters afgenomen van personen met IAZ en 220 monsters van mensen met een ARI.
• In de IAZ monsters werd 19 maal een influenzavirus gevonden; 7 maal (37%) type A(H1N1)pdm09, 9 maal (47%) type A(H3N2) en 3 maal (16%) type B (Yamagata-lijn).
• In de ARI monsters werd 11 maal een influenzavirus gevonden; 3 maal (27%) type A(H1N1)pdm09, 1 maal (9%) influenzavirus type A(H3N2) en 7 maal (64%) type B (Yamagata-lijn).
http://www.rivm.nl/Onderwerpen/Ziekt...ningen/G/Griep

The dutch flu season test results so far:
Data 1 october 2012 - 30 december 2012
140 swaps from people with ILI (Influenza like illness)
220 swaps from people with ARI (Acute respiratory infections)

ILI set
19 of 140 positive for influenza
7 or 37% type A(H1N1)pdm09
9 47% type A(H3N2)
3 Flu B

ARI set
11 influenza positives
3 or 27% type A(H1N1)pdm09
1 or 9% type A(H3N2)
7 or 64% type B (Yamagata).

Our ILI set alreay looks a lot like the US.

Mind you numbers are low so one positive can change stuff. Not sure if all sampling from last week of 2012 has been finished.

It would be interesting to recheck in some weeks.
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