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Old 09-08-2013, 01:45 PM   #1
Potemkin
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Default Quadrivalent flu vaccines

So what is the skinny on quadrivalents coming out this year?

Fluzone Quadrivalent, Fluarix Quadrivalent and FluLaval Quadrivalent

Good for someone who makes frequent trips to Asia and get off the beaten path?

http://www.chron.com/news/medical/ar...pid=healthhcat

No egg versions, quad dose versions, subdermals, all kinds of new things coming out.
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Old 09-08-2013, 05:32 PM   #2
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http://www.cdc.gov/flu/professionals...mendations.htm

Quote:
◦A quadrivalent live attenuated influenza vaccine (LAIV4; Flumist® Quadrivalent [MedImmune]) is expected to replace the trivalent (LAIV3) formulation. FluMist® Quadrivalent is indicated for healthy, nonpregnant persons aged 2 through 49 years;
I can't get it..,

It looks like the attenuated version is available for 3 and up..,
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Old 09-08-2013, 06:27 PM   #3
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I think the quad has two 'B' strains but I'm not certain & I'll check.
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Old 09-09-2013, 10:24 AM   #4
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GSK Wins FDA OK for Quad Flu Vaccine

Published: Dec 17, 2012

By Michael Smith , North American Correspondent, MedPage Today



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The FDA has given the nod to another influenza vaccine intended to protect against four strains of the virus, according to the drug's maker.
The vaccine -- dubbed Fluarix Quadrivalent -- will be available for the 2013-2014 flu season, according to a release from GlaxoSmithKline (GSK), of London, England.
Unlike current trivalent vaccines, it will include two strains of influenza B, as well as the standard two strains of influenza A.
The GSK drug is one of a number of quadrivalent vaccines under development; another is being produced by Sanofi Pasteur of Swiftwater, Pa., and has not yet been approved.
The first such vaccine to be approved -- FluMist Quadrivalent, an attenuated live-virus vaccine made by Medimmune of Gaithersburg, Md. -- got the FDA OK Feb. 29.
Two main lineages of influenza B -- dubbed Victoria and Yamagata -- have been circulating for more than a decade, and choosing which one to include in the annual flu vaccine has been a guessing game.
Panels of experts choose what strains of the flu they expect to circulate in any given year, and vaccines are manufactured to include those strains. But because vaccine manufacture takes time, the decision must be made months before flu season actually starts.
If a seasonal flu vaccine has a B strain that is mismatched against the circulating strain, it offers little or no protection against disease caused by influenza B.
Indeed, the company release noted, "various degrees of mismatch have occurred between the B strain included in trivalent vaccines and the B strain that actually circulated, causing an increased risk of influenza-related morbidity across all age groups -- children, adults and the elderly."
In fact, the company noted, in six of the last 11 flu seasons, the predominant circulating influenza B strain was not selected by public health authorities and included in that year's vaccine.


http://www.medpagetoday.com/Infectio...RItheFlu/36487
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Old 09-09-2013, 11:54 AM   #5
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I like the fact they're including the 2 major 'B' strains. It IS a guessing game every year & every year there are regions where the non-vax strain goes crazy.

While 'B' is generally milder, that's not always the case & when that's YOUR baby or Very Small so ill, it can be terrifying. It can also lead to far more serious complications & I don't care what anti-vax types say, the economic losses from caring for sick kids at home are not negligable.
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Old 10-02-2013, 09:44 AM   #6
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I found the GlaxoSmithKline quadravalent at Walgreens pharmacy.

Free immunization for employees of my company.

Woot.

No high dose allowed at my age.
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Old 10-08-2013, 11:43 PM   #7
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BTW, the arm hurt more. I don't know if it was because I have less "mass" there or not.

Usually I feel a little draggy for 24 hours, not this time.
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Old 10-09-2013, 01:25 AM   #8
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Quote:
Originally Posted by CanadaSue View Post
I think the quad has two 'B' strains but I'm not certain & I'll check.
2 A and 2 B. tri has 2 A and 1 B.
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