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Old 04-14-2014, 07:05 PM   #1
Justathought
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Default Ebola Outbreak in Guinea

CNN - 3 hours ago (4/13/14) "This time, the outbreak is different. In the past, Ebola rarely made it out of the remote forested areas of Africa."

http://www.cnn.com/2014/04/14/health...nea/?hpt=he_c1

Ebola is in Conakry now, the capital city of Guinea, with two million residents and an international airport nearby. Yesterday (Sunday, 4/13/14) on CNN, Dr. Sanjay Gupta (in Conakry) said that this outbreak is spreading farther and faster than ever before. Victems must show signs of illness before they are contageous. The incabation periord of Ebola is long (from two to twenty one days).

With a CFR of 50% to 90%, I Hope Sanjay is quarentined when he comes home to New York.


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Old 04-16-2014, 04:00 AM   #2
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"on CNN, Dr. Sanjay Gupta "

Yeah, Dr G looked 'stressed out'..
?what, maybe jet lag.?

ah NO.
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Old 04-22-2014, 07:58 PM   #3
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Can any-one here read "Italian"......... might be important

http://www.vnews24.it/2014/04/19/ebola-epidemia-italia/
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Old 04-22-2014, 08:06 PM   #4
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Let me take a half assed crack at it... knowing French often works.
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Old 04-22-2014, 08:11 PM   #5
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It's the same report being circulated 'everywhere' - 40 illegal immigrants with mild fever now quarantined at the reception center where they ended up. Mention of unspecified 'strange' symptoms.

No official confirmation or denial.
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Old 04-22-2014, 08:12 PM   #6
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Google translate of the article sorry its not very good









April 19, 2014 - FYI , Milan , Rome, Italy - Raffaella De Grazia - Tags : alarm, Ebola virus

Ebola outbreak : 40 cases registered in Italy , Rome and Milan equipped






Ebola





And ' mystery about forty hypothetical cases of Ebola registered in our country . The virus is particularly common on the African continent - the cases "official" were recorded in Senegal , Mali and Ghana - may have arrived in Italy "thank you" to the massive exodus of immigrants to our shores . A first " bell " d ' alarm was launched by Lampedusa. According to a report appeared in the network ( and immediately removed for reasons of "national security" ), in fact, April 16 would be recorded on an epidemic ' island , never confirmed nor refuted by our Ministry of Health.



READ ALSO: " He died of a cancer in two Italian " oncologist launches national alarm



A new "SOS" about the spread of the virus ' Ebola in the Bel Paese is , this time , from Tuscany. Means of dissemination of the news shock is always the network : blogs, social networks , websites dedicated highlighted the " Curious Case of St. Flushing ," reception center site in Pisa , closed to the public due to the presence , all 'inside of it, forty non-EU nationals which are to some strange symptoms. Sandra Capuzzi , Councillor for Social Policies of the Municipality of Pisa, he would have dismissed the alarmism of his countrymen , by classifying the health status of the refugees in the structure in these terms: " They just have a little fever, caused by stressful travel conditions under which the boys have been subjected . " Will this really happen ?



READ ALSO: Meningitis killer : 11 year old girl dies in Lodi



Echoes the comment of Capuzzi confident that the President of the Italian Red Cross of Pisa, Antonio Cerrai . On the Facebook profile of ' Councillor of Pisa, Cerrai commented on the rumors about a possible spread of ' Ebola in the Tuscan city : "All ' ignorance is answered with knowledge ," was the dry " incipit " of the statements made by the President of CRI Pisano , who explained how , in the remote case of danger of the spread of ' Ebola in Italy , the ships of the Italian Navy in charge of the landing of the refugees on our shores would not allow any passenger to board the boats to leave .

Fear , meanwhile, remains . The forty possible carriers of the virus ' Ebola have been subjected to all the tests required in high-risk situations . The Italian population , however, does not feel the climate of reassurance that high institutional positions and subjected try to transmit information through various channels , official and unofficial . The tension increases, although the Ministry of Health said that , in the unlikely event of an outbreak , Rome and Milan would be ready to face the ' epidemic.

The first appearance of the ' Ebola in 1976 in the Democratic Republic of Congo. Currently , experts have isolated four strains of the virus, three of which have proved fatal for the ' man . The disease can be transmitted to ' human infection by animal , and then can spread through contact with infected blood and body fluids . The symptoms of ' Ebola are quite common and not easily recognizable , in part haemorrhagic fever , which is a sort of " final stage " of the virus. L ' Ebola initially may manifest as fever simple , vomiting, diarrhea , malaise . Waiting for an official denial by the Ministry of Health, the ' alarm Ebola in our country remains high .
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Old 04-22-2014, 08:24 PM   #7
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That's more detail than I got but some of the reporting is flat out wrong. Mali, Senegal & Ghana do NOT have cases. Mali at least - not sure about the other two - had a suspected case who tested out negative.
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Old 04-28-2014, 05:29 AM   #8
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Quote:
Originally Posted by CanadaSue;
'It's the same report being circulated 'everywhere' - 40 illegal immigrants with mild fever now quarantined at the reception center where they ended up. Mention of unspecified 'strange' symptoms. No official confirmation or denial.
'strange' symptoms'? Like spontanious bleeding from every oraface? Apparently this virus jiggers the body's clotting mechanisum; veins and blood pathways inside the body start to clot up and still normal blood vessels, etc. rupture from increasing pressure as the heart and lungs work like bellows trying to force blood (and oxygen) through the body to keep it alive. In the meantime the "freed" blood leaks out however it can (eyes, nose, mouth, etc.). No wonder most infected die!

OK, that is the Bad News, the Good News is that so far, Ebola is an "infection by contact" only virus. It is not "airborne". Also victems are not infectious until disease symptoms appear (takes 2 to 21 days), and by then they are dying and seldom mobile.

On the other hand, this is not the usual Ebola! The WHO in partnership with Doctors without Borders has been putting out Ebola outbreaks in Africa for years and they have time proven, successful protocals to treat this disease.

This virus is different! At the very least it has escaped the usual well established Ebola quarantine system. Whatever else it is, was enough to seriously alarm a usually brave, unflapable Dr. Sanjay (something the Doctors treating the Ebola victems told him?). At the same time, other news outlets seem to have dryed up. More "don't scare the sheep" stuff? Now that is concerning......

Makes one wonder just how much this strain of Ebola may have changed.

Quote:
From the CDC: Ebola Hemorrhagic Fever Highlights

April 20, 2014, the Guinea Ministry of Health announced a total of 208 suspect and confirmed cases of Ebola hemorrhagic fever (EHF), including 136 deaths, in the districts of Guékédou, Macenta, Kissidougou, Dabola, Djingaraye, and Conakry, the capital. (See map)

112 cases in Guinea have been confirmed by laboratory testing to be positive for Ebola virus infection.

In Conakry, 53 suspect cases have been reported to meet the clinical definition for EHF, including 23 deaths. 25 health care workers in Guinea have been reported with clinical symptoms of EHF; 18/24 are laboratory confirmed cases and 16/24 patients have died.

As of April 21, 2014, the Ministry of Health and Social Welfare of Liberia reported 34 suspect cases, including 11 deaths, across the country.

Genetic analysis of the virus indicates that it is closely related (97% identical) to variants of Ebola virus (species Zaire ebolavirus) identified earlier in the Democratic Republic of the Congo and Gabon (Baize et al. 2014).

The Guinean Ministry of Health and the Ministry of Health and Social Welfare of Liberia are working with national and international partners to investigate and respond to the outbreak.

Outbreak Update, April 23, 2014

The Ministry of Health (MoH) of Guinea’s reported 208 suspect and confirmed cases of Ebola hemorrhagic fever (EHF), including 136 deaths, on April 20, 2014 according to the World Health Organization (WHO). Of these suspect cases, 112 have been laboratory confirmed positive cases of Ebola hemorrhagic fever (EHF). One additional health care worker has been reported among the suspect and confirmed cases bringing the total to 25, including 16 deaths. Other districts reporting suspect and confirmed cases remain Guekedou, Macenta, Kissidougou, Dabola, and Djingaraye.

WHO reports that the Ministry of Health and Social Welfare (MOHSW) of Liberia announced the cumulative total of suspect and confirmed cases of EHF is 34, including 11 deaths, on April 21, 2014. Six (6) samples have tested positive for Ebola virus. Samples from Mali and Sierra Leone have, thus far, been negative for Ebola virus though investigations and monitoring of reports of suspect cases is ongoing.

Médecins sans Frontières (MSF/Doctors without Borders) is helping the Ministry of Health of Guinea in establishing treatment and isolation centers in the epicenter of the outbreak. In Liberia, several international organizations including the International Red Cross (IRC), Pentecostal Mission Unlimited (PMU)-Liberia, and Samaritan’s Purse (SP) Liberia are aiding the MOHSW of Liberia by supporting awareness campaigns and providing personal protective equipment (PPE) for healthcare workers.

The Institute Pasteur in Lyon, France, the Institut Pasteur in Dakar, Senegal, the European Consortium mobile laboratory, and the Metabiota supported laboratory in Kenema (Sierra Leone) and Monrovia (Liberia), and CDC Atlanta are some of the laboratories collaborating to test samples. CDC is in regular communication with its international partners, WHO, and MSF regarding the outbreak.

Currently CDC has a 7 person team in Guinea and a 3 person team in Liberia assisting the respective MOHs and the WHO-led international response to this Ebola outbreak.

Based on WHO update 22 April 2014.

http://www.cdc.gov/vhf/ebola/outbreaks/guinea/
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Old 04-28-2014, 06:26 AM   #9
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The 'strange' symptoms weren't specified. There hasn't been a word about the Italian situation since it was first splashed across a few sites.

This strain of Ebola - the outbreak pattern is different but the virus itself isn't, (not reportedly yet), showing significant changes in symptoms, transmissibility, outcomes... it simply has a wider geographic spread.

The outbreak is also slowing down significantly. As of April 23rd, 141 cases have proven fatal, from 218 cases in Guinea. 4 of the 6 communities that reported cases have had no new cases for 21 days - one 'full' potential incubation cycle. Liberia reports a total of 35 confirmed/suspected cases. Sierra Leone is currently checking out 3 potential cases but they've had none yet.

Par for the course for one of these outbreaks so far - save for the initial dispersal of a few patients.
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Old 04-29-2014, 11:06 PM   #10
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I agree it is early days yet but something to watch. The CDC says this strain of Ebola is 97% the same as a previously known strain. The Devil is in the details of the remaining 3%...

I wonder if the incubation period has been expanded in this strain? That would enable it to "outlive" the currently established Ebola quarantine period. On the other hand, perhaps none of those migrating Ebola victems were ever quarantined in the first place.

Time will tell.

Dr. Niman has reported nothing about this current Ebola outbreak which is uncharacteristic.

One good thing; the spread of this outbreak is bound to shake things up and put new money and renewed interest in finding an effective vaccine.

Letting this deadly virus simmer year after year in Africa, while it improves itself with an eye to sweeping through Billions of human hosts (killing most of them) makes no sense.


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Old 04-29-2014, 11:15 PM   #11
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All you wanted to know about the Ebola Virus (and more) from the U.S. CDC Ebola Homepage:

http://www.cdc.gov/vhf/ebola/index.html


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Old 04-29-2014, 11:19 PM   #12
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The thought of this one ever going airborne scares the poop out of me. It would be beyond horror.

I'm surprised Dr. Niman hasn't posted on it.
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Old 05-02-2014, 03:43 AM   #13
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A mysterious disease has killed 14 in a week in a remote area of Pakistan

http://www.dawn.com/news/1103621/mys...omen-in-bajaur
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Old 05-02-2014, 09:24 AM   #14
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Quote:
Originally Posted by Malcolm View Post
A mysterious disease has killed 14 in a week in a remote area of Pakistan

http://www.dawn.com/news/1103621/mys...omen-in-bajaur
Could be MERS
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Old 05-02-2014, 09:37 AM   #15
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So little info in that article, no symptoms reported.
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Old 05-02-2014, 11:59 AM   #16
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Quote:
Originally Posted by CanadaSue View Post
I'm surprised Dr. Niman hasn't posted on it.
Watch what you wish for!!!!

I think about Niman all the time. He is different, and of great value. But he is very different.
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Old 05-02-2014, 01:04 PM   #17
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I said I was surpised - not heartbroken...LOL

Pakistan... women between the ages of 40-50, all in good health before falling ill. Those dying die a short time after falling ill. That's all we've got to go on. No symptoms, no epidemiology; no knowledge of improvement or recovery among any of the women taken ill.

It doesn't sound like an infectious disease to me - the age range & sex... too narrow. Unless it's an odd illness where only a very specific demographic become visibly ILL while others may be infected & not show symptoms.

Hard to figure out though - what do women of that age do that other women or men, boys or girls do?

Odd.
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Old 05-02-2014, 02:47 PM   #18
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Hard to figure out though - what do women of that age do that other women or men, boys or girls do?
Go through menopause?
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Old 05-02-2014, 03:43 PM   #19
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The women in their 40's in a tiny, highly religious village are probably friends. Could be anything. They all went to the same ritual cleansing bath and got a disease from standing water, they all ate bad food, etc.etc.
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Old 05-05-2014, 07:25 PM   #20
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Good News...No New Cases of Ebola and the CDC website is quiet...

Quote:
Ebola outbreak under control, says Guinea president
May 01, 2014 - Updated 1526 PKT

GENEVA: Guinea's Ebola outbreak is under control, but the death toll could rise above the current 74 because sick patients remain in hospital, the president said Wednesday.

"For the moment the situation is well in hand, and we touch wood that there won't be any new cases," President Alpha Conde told reporters during a visit to Geneva, home of the World Health Organization (WHO).

However he warned that with a number of people still in hospital suspected to be suffering from the deadly virus, the death toll may yet rise.

"There haven't been any new cases. But of those who remain in quarantine, there certainly will be some who will die," he said.

Working with the UN health agency and aid groups, Guinea remains on high alert against the virus, an incurable disease that can kill up to 90 percent of its victims.

On Tuesday, the health ministry said that 74 people had died so far this year in one of the worst ever outbreaks of the virus, with 121 confirmed cases. A larger number of people have been diagnosed with haemorrhagic fever, but not all those cases have been confirmed as Ebola.

No new cases have been recorded since Sunday, although four people are receiving treatment in the capital Conakry, and six in Gueckedou, in the south, which has seen one of the most serious outbreaks.

There is no vaccine or cure for Ebola, which can be caught from handling the blood or the bodily fluids of sick or dead forest animals.

Researchers in the United States have confirmed that the Guinea outbreak began after contact with bats caught for their meat in the country's southern forests, Conde noted.

It then spread in the hunters' communities and to health workers who initially failed to identify the risk posed by feverish patients.

To try and limit the outbreak, the government has advised Guineans to stop eating bats and avoid other "bush meat" when possible, and has also striven to apply infection-control measures by monitoring potential cases and those they have come into contact with.

The disease has spread to neighbouring Liberia, with suspected cases reported in Mali and Sierra Leone sparking fears it could spread throughout the region.

But in a sign of subsiding concerns, Senegal, which had closed its border with Guinea, reopened the frontier on Tuesday, Conde said.

The WHO has described the outbreak as one of the most challenging since the virus emerged in 1976 in what is now the Democratic Republic of Congo.

Ebola leads to haemorrhagic fever, causing muscle pain, weakness, vomiting, diarrhoea and, in severe cases, organ failure and unstoppable bleeding.

There is no vaccine or cure for the virus, which can easily spread among humans through contact with infected blood, bodily fluids and tissue.

Its spread can be stopped only by isolating suspected cases in ultra-clean conditions and quarantining those who have been in contact with them.

http://www.thenews.com.pk/article-14...inea-president

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Old 08-01-2014, 05:52 AM   #21
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Originally Posted by CanadaSue View Post
The thought of this one ever going airborne scares the poop out of me. It would be beyond horror.

I'm surprised Dr. Niman hasn't posted on it.
Looks lilke the latest "not to worry" report from the CDC has spured Dr. Niman to start analyzing this outbreak:

Quote:
Novel Zaire Ebola Sub-Clade In Guinea and Sierra Leone
Recombinomics Commentary, July 29, 2014

The Infectious Disease Initiative at the Broad Institute of MIT and Harvard, which is part of the Viral Hemorrhagic Fever Consortium, has released 84 complete or nearly complete Ebola sequences (at Genbank – EBOV_1 – EBOV_84 with accession numbers KM233035 – KM233118) from Sierra Leone patient collections between June 2 and June 12, 2014. These sequences follow the release of 14 Sierra Leone sequences by the same group sequencing samples collected on June 1.

Thus, they have made public 98 sequences from collections in the first 12 days in June, 2014. They are commended for the rapid release of these important sequences, which are closely related to three full sets of sequences from three Guinea cases collected in March, 2014 from two distinct locations, Gueckedou (Gueckedou-C05 and Gueckedou-C07) and Kissidougou (Kissidougou-C15).

All 101 sequences form a Zaire sub-clade which signals clonal expansion due to human to human transmission following a single introduction. These 101 sequences are easily distinguished from all other Zaire sub-clades, which have been associated with the largest number of reported Ebola outbreaks, including the previously most deadly outbreak in Yambuku, Zaire in 1976 (280 deaths in 318 cases), which was followed by the second most deadly outbreak, which was 19 years later in Kikwit, Zaire in 1995 (245 deaths in 317cases). The current outbreak, which is again 19 years later but in Guinea, Sierra Leone, and Liberia, has already produced more reported deaths (672 deaths in 1201 cases) than the two earlier outbreaks combined and comments made in yesterday’s US CDC Ebola telebriefing suggests there is no end in sight.

The CDC telebriefing and Ebola HAN advisory comes after the death of a naturalized American who traveled to Lagos, Nigeria from Monrovia, Liberia and the hospitalization of two American healthcare workers, also in Liberia. The CDC had noted that Ebola was only one flight away from the United States, and the fatal case had planned on flying to Minnesota in two weeks for his daughter’s birthday.

The June Sierra Leone sequences have evidence of some drift from the March sequences from Guinea. A prior Zaire sub-clade, which was found in apes and a chimpanzee and was associated with an outbreak in Gabon in 2002 had strong evidence of recombination, which raises concerns of more evolution in the current sub-clade, which has produced a record number of reported Ebola cases and deaths.
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Old 08-04-2014, 11:38 PM   #22
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As of yesterday, there were two Ebola threads running on this site; a major,Ebola Thread of about 15 pages of posts and a newer, shorter Ebola Thread in the "Flu Clinic" with just a few pages of posts. I just got home and it looks like "Flu Clinic" Ebola Threads have sproted like Toad Stools. If interested, here is the link to the major Ebola Thread in the Flu Clinic:

http://thisbluemarble.com/showthread...211#post464211

NOW, regarding who got what drug, serum, or vaccine. Here is some information/speculation from the Health and Medicine "Ebola" Forum:

Quote:
From Catbird yesterday:"wonder if we'll see some detail on what was used."

Canadian-made experimental Ebola drug not used on U.S. missionary

From Helen Branswell, The Canadian Press Aug 3, 2014:

Quote:
The Canadian company that is developing an experimental Ebola drug says its product was not given to one of two American aid workers infected with the virus.

Tekmira Pharmaceuticals said in an email that no one infected in the ongoing outbreak in West Africa has been treated with its drug, called TKM-Ebola...

Quote:
From Justathought, yesterday: "Maybe the best thing to come out of CNN this morning about Ebola is the information that before Dr. Bradley left for the U.S., he received a blood transfussion from a young man/boy who he had treated for Ebola and who had recovered.

Bradley needed blood to travel on anyway, and it was hoped there might be antibodies still in it that would help him. After reading the pre-travel reports, I don't think anyone expected him to be able to enter Emery on his own two feet.

One of the problems the CDC and Emory might have, is in an effort to find/verify a sucessful treatment or cure, they "over medicate" Dr. Bradley and if he survives, no one will know why...

Also, CNN interviewed some drug company rep. who said they have offered three possible Ebola treatments to the CDC "fast track" process: An immune system drug, a protein balancing something-something, and a Post Ebola infection vaccine (something like the post rabbies vaccine). This guy was definately a salesman type with dollar signs in his eyes.

He won't be the only one. With new DOD, etc. money to play with, lets hope something real shows up."

Up to that point, the media and the CDC had reported that only one dose of an experimental "serum" was availlbe and Dr. Bradley had insisted that it be given to his sick co-worker. Of course, remember, he received that blood transfusion with possible antibodies in it. Now CNN reports that both Dr. Bradley and his co-worker were given doses of something else. They both seem to be recovering, but no one knows why.

Research run amuck? All will be clear in time, it is early days yet.
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Old 08-04-2014, 11:47 PM   #23
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Let's keep the Ebola stuff in the Ebola forum, rather than spreading it all over the site. Thread closed.
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Old 08-05-2014, 04:49 AM   #24
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I just moved this to the Ebola forum, and re-opened it.
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Old 08-14-2014, 12:40 AM   #25
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Quote:
Guinea declares emergency over Ebola

14 AUG 2014 - 2:20PM

Guinea has declared an Ebola outbreak that has killed 377 in the nation a "health emergency" and more flights from hard-hit west African countries have been cancelled as the region awaited shipments of an experimental vaccine.

Guinean President Alpha Conde on Wednesday announced a series of measures including strict controls at border points, travel restrictions and a ban on moving bodies "from one town to another until the end of the epidemic".

In addition all suspected victims will automatically be hospitalised until they are cleared of infection, Conde said.

As the region scrambled to halt the spread of the virus, Gambia suspended all flights from Guinea, Liberia and Sierra Leone, according to a transport ministry document obtained by AFP on Wednesday.
http://www.sbs.com.au/news/article/2...cy-over-ebola?
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