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Old 10-07-2015, 11:28 AM   #26
gsgs
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did you see the study about the flu vax not being as effective as they thought?
## no. what strain ? do they already know what strain USA will get
** vax cuts the risk of H3N2 by an average of only 38%

Branswell tweeted about it



http://www.bostonglobe.com/lifestyle...?event=event25

http://www.cdc.gov/flu/weekly/weekly...s/image381.gif


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but that's apparently not the vaccine for this season. It's a study
about the previous seasons. We knew that already.
The H3-component is changed now.

=============================================

http://www.who.int/influenza/vaccine...tion201509/en/

the 2016 Southern recommendation recommendation paper is out

an A/California/7/2009 (H1N1)pdm09-like virus;
an A/Hong Kong/4801/2014 (H3N2)-like virus;
a B/Brisbane/60/2008-like virus.


http://www.who.int/influenza/vaccine...ation.pdf?ua=1

A(H3N2) viruses collected from February 2015 to August 2015 fell into the phylogenetic
clades 3C.2 and 3C.3. Viruses in sub-clade 3C.2a are now predominant in all regions
of the world. Sub-clade 3C.3a and 3C.3b viruses continued to circulate but represented
the minority of viruses in this reporting period.
Antigenic characteristics of A(H3N2) viruses were assessed with panels of post-infection
ferret antisera in HI and virus neutralization assays. Antigenic characterization of 3C.2a
viruses remained technically challenging because many viruses had low or undetectable
haemagglutination activity and required the use of modified HI and virus neutralization
assays for analysis. Most recent A(H3N2) 3C.2a viruses were well inhibited by ferret
antisera raised against cell-propagated reference
A/Switzerland/9715293/2013 (3C.3a) virus, indicating that 3C.2a and 3C.3a viruses
remain antigenically related. Ferret antisera raised against reference cell-propagated
3C.2a viruses also well inhibited a majority of viruses tested, although inhibition was
somewhat reduced against 3C.3a viruses, indicating that some 3C.2a and 3C.3a
viruses were antigenically distinguishable.
Such changes have been particularly problematic for recent A(H3N2) viruses.
Ferret antisera raised against egg-propagated 3C.2a viruses, including
A/Hong Kong/4801/2014, generally inhibited recently circulating
viruses better than antisera raised to egg-propagated
A/Switzerland/9715293/2013 virus (Table 1).

A/Moldova/111.07/2015 , 3C.2a ,2015-02-10 ,80
A/South Africa/R3777/2015 ,3C.2a ,2015-06-26 ,80
A/South Africa/R3803/2015 ,3C.2a ,2015-06-29 ,80
A/South Africa/R3778/2015 ,3C.2a ,2015-06-29 ,40
A/Iasi/177050/2015 ,3C.3a ,2015-02-04 ,40
A/Behoririka/355/2015 ,3C.3a ,2015-02-04 ,40
A/Manjakaray/612/2015 ,3C.3a ,2015-02-23 ,80
A/Stockholm/19/2015 ,3C.3b ,2015-02-25 ,80
A/Sweden/16/2015 ,3C.3b , 2015/03/05 ,160


80,40 is not so very good



Egg propagation is known to introduce additional changes that may affect antigenicity.

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http://www.flunewseurope.org/

5B,2H3,5H1,5A? in Europe so far

week 40, Europe, .pdf , 7 pages : http://www.flunewseurope.org/Archives/GetFile?fileId=94

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Last edited by gsgs; 10-09-2015 at 11:31 AM.
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Old 10-15-2015, 12:10 PM   #27
Arianwen
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We got our vaccination, me and DS got FluMist (he was being uncooperative lol.) Everyone seems OK. I was a bit congested but I'll take that over a pokey any day.

Eta: achoo, achoo, achoo, cough.

Last edited by Arianwen; 10-15-2015 at 05:25 PM.
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Old 10-28-2015, 09:47 AM   #28
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A/Hong Kong/7295/2014 looks best in their table 3 at
http://www.who.int/entity/influenza/...mmendation.pdf

so why did they choose A/Hong Kong/4801/2014 instead ?

Northern Hemisphere has
A/Switzerland/9715293/2013 (H3N2)-
for 2015/16


===============================================

surveillance 2015/6:
http://www.cdc.gov/flu/weekly
http://afhsc.army.mil/Reports/DoDWeekly
http://www.flunewseurope.org/

Europe:
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Last edited by gsgs; 11-07-2015 at 01:58 AM.
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